Nigerian Hospital Launches Groundbreaking Bone Marrow Transplant Program for Sickle Cell Patients

In a notable advancement for sickle cell disease (SCD) treatment, the Lagos University Teaching Hospital (LUTH) has officially launched the country’s first bone marrow transplant program tailored specifically for SCD patients. This initiative, developed in partnership with the Sickle Cell Foundation Nigeria (SCFN), aims to provide local access to this critical procedure.

The first group of patients admitted in August is currently undergoing transplants, with procedures carried out between September 17 and 19. These patients received preparatory treatments including exchange blood transfusions, chemotherapy, and anti-infective prophylaxis to ensure their readiness for the transplant.

According to a joint statement from LUTH’s Chief Medical Director, Professor Wasiu Adeyemo, and SCFN’s National Director/CEO, Annette Akinsete, the program addresses significant gaps in the existing care landscape for sickle cell patients in Nigeria. “The establishment of this program is a direct response to the urgent need for effective treatments within the country,” Adeyemo said.

Nigeria has the highest prevalence of sickle cell disease globally, with approximately 150,000 new cases each year. The World Health Organization (WHO) estimates that 24% of the Nigerian population are carriers of the sickle cell trait, leading to an alarming number of fatalities—over 100,000 babies die annually from SCD complications.

Despite the risks associated with bone marrow transplants, including infection and potential infertility, recent advancements have markedly improved patient outcomes. The new program at LUTH adheres to international standards, ensuring that it meets the necessary medical protocols for patient safety and efficacy.

The initiative has been bolstered by expertise from international professionals, including a resource specialist from Imperial College London, Josu de la Fuente, who has contributed to the program’s pediatric components.

To further support this initiative, LUTH established a post-transplant clinic in 2019, becoming the first in sub-Saharan Africa to offer specialized care for patients returning from abroad for transplants. This development has been instrumental in cultivating local expertise and improving care standards for those affected by SCD.